rat anti-mouse lamp1 antibody Search Results


rat anti-mouse lamp1 antibody  (Biocare Medical)
90
Biocare Medical rat anti-mouse lamp1 antibody
( A ) GAA and glycogen levels were assessed in tissue lysates prepared from heart and gastrocnemius of 12-week old male Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mice. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO and Gaa KO mice compared to wild-type mice are reported as *p<0.05, t-test. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO mice compared to Gaa KO mice are reported as # p<0.05, t-test. Each bar represents the mean ± SEM from four mice per group analyzed in triplicate. Glycogen accumulation ( B ) and lysosomal proliferation (assessed by the quantity of <t>LAMP1)</t> ( C ) were assessed histochemically in Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mouse cardiomyocytes and skeletal muscles fibers of the gastrocnemius. Glycogen staining is represented as dark pink spots, and LAMP1 staining as dark brown spots (each denoted with black arrows). The data shown are representative photomicrographs from four mice using a 40× (scale bar: 50 µm) or 20× (scale bar: 100 µm) objective in ( B ) and ( C ), respectively.
Rat Anti Mouse Lamp1 Antibody, supplied by Biocare Medical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
rat anti-mouse lamp1 antibody - by Bioz Stars, 2026-02
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( A ) GAA and glycogen levels were assessed in tissue lysates prepared from heart and gastrocnemius of 12-week old male Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mice. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO and Gaa KO mice compared to wild-type mice are reported as *p<0.05, t-test. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO mice compared to Gaa KO mice are reported as # p<0.05, t-test. Each bar represents the mean ± SEM from four mice per group analyzed in triplicate. Glycogen accumulation ( B ) and lysosomal proliferation (assessed by the quantity of LAMP1) ( C ) were assessed histochemically in Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mouse cardiomyocytes and skeletal muscles fibers of the gastrocnemius. Glycogen staining is represented as dark pink spots, and LAMP1 staining as dark brown spots (each denoted with black arrows). The data shown are representative photomicrographs from four mice using a 40× (scale bar: 50 µm) or 20× (scale bar: 100 µm) objective in ( B ) and ( C ), respectively.

Journal: PLoS ONE

Article Title: The Pharmacological Chaperone AT2220 Increases the Specific Activity and Lysosomal Delivery of Mutant Acid Alpha-Glucosidase, and Promotes Glycogen Reduction in a Transgenic Mouse Model of Pompe Disease

doi: 10.1371/journal.pone.0102092

Figure Lengend Snippet: ( A ) GAA and glycogen levels were assessed in tissue lysates prepared from heart and gastrocnemius of 12-week old male Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mice. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO and Gaa KO mice compared to wild-type mice are reported as *p<0.05, t-test. Significant differences in GAA activity and glycogen levels in hP545L GAA Tg/KO mice compared to Gaa KO mice are reported as # p<0.05, t-test. Each bar represents the mean ± SEM from four mice per group analyzed in triplicate. Glycogen accumulation ( B ) and lysosomal proliferation (assessed by the quantity of LAMP1) ( C ) were assessed histochemically in Gaa KO, hP545L GAA Tg/KO, and wild-type (denoted as ‘WT’ in the figure) mouse cardiomyocytes and skeletal muscles fibers of the gastrocnemius. Glycogen staining is represented as dark pink spots, and LAMP1 staining as dark brown spots (each denoted with black arrows). The data shown are representative photomicrographs from four mice using a 40× (scale bar: 50 µm) or 20× (scale bar: 100 µm) objective in ( B ) and ( C ), respectively.

Article Snippet: After an overnight incubation with a rat anti-mouse LAMP1 antibody (1∶500 dilution) at 4°C, sections were incubated with components from the Promark rat-on-mouse HRP-polymer kit (Biocare Medical); stain was developed with a Betazoid DAB kit (Biocare Medical).

Techniques: Activity Assay, Muscles, Staining